In her thesis ‘Advanced simulation of an operating room: from the virtual model to the digital twin’ Giovanna Gargiulo used Digital Twin (DT) in an operating theatre to study airflows and prevent post-surgery infections. The advantage of DT is the capability to manage the variables of interest associated with any change in the room conditions and to control the air quality in real time. Many scenarios simulated by CFD are used to train a Reduced Order Model (ROM) and obtain from this a DT, which monitors the air quality and improves it by means of managing multiple sets of parameters (e.g., temperature, pressure, velocity inlet, position of the medical staff and patient). The DT evaluates, in real-time and without adding further CFD simulations, any change in the room conditions not previously simulated by CFD.

Here you can read the presentation and the full thesis.